Scotland head coach Gregor Townsend has made three changes for the trip to Rome from the win over England. Centre Sione Tuipulotu is injured so Bath’s Cam Redpath replaces him.
At scrum-half George Horne comes in for Ben White whilst Saracens’ Andy Christie replaces former captain Jamie Ritchie in the back-row.
Scotland: Kinghorn, Steyn, Jones, Redpath, Van der Merwe, Russell (co-capt), Horne; Schoeman, Turner, Z Fagerson, Gilchrist, Cummings, Christie, Darge (co-capt), Dempsey.
Replacements: Ashman, Hepburn, Millar-Mills, Skinner, Ritchie, M Fagerson, Price, Rowe.
Italy have made three changes from the draw against France. There is a debut for wing Louis Lynagh, the son of Australia great Michael.
Tommaso Menoncello moves back to centre and Federico Mori drops to the bench.
Flanker Sebastian Negri returns after missing two games through injury and prop Simone Ferrari comes in for Giosue Zilocchi.
Italy: Capuozzo, Lynagh, Brex, Menoncello, Ioane, Garbisi, Page-Relo; Fischetti, Nicotera, Ferrari, Cannone, Ruzza, Negri, Lamaro (captain), Vintcent.
Replacements: Lucchesi, Spagnolo, Zilocchi, Zambonin, Cannone, Varney, Marin, Mori.